Compound Overview

Melanotan 2 is a synthetic cyclic heptapeptide and a lactam-constrained analogue of α-melanotropin. It is identified in the literature as MT-II and is used as a melanocortin receptor agonist in laboratory research.

This material is supplied as a laboratory research reagent intended for controlled experimental environments, including melanocortin receptor binding studies, cAMP-based signaling assays, and structure-activity investigations involving cyclic melanocortin ligands.

Molecular Information

Compound Type: Synthetic cyclic heptapeptide
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Molecular Formula: C₅₀H₆₉N₁₅O₉
Molecular Weight: 1024.18
CAS Number: 121062-08-6
Purity: 99.30%

Research Applications

Melanotan 2 appears in published laboratory studies as a melanocortin receptor agonist used to examine receptor binding, subtype activity, and downstream signaling responses. It is also used in structure-function and structure-activity studies centered on cyclic α-MSH analogue design.

Agonist ligand in melanocortin receptor binding studies
cAMP accumulation assays at recombinant melanocortin receptors
Subtype activity profiling across melanocortin receptor panels
Structure-function studies on the MT-II peptide scaffold
Structure-activity relationship studies of cyclic α-MSH analogues
Peptide design studies evaluating alternative cyclization motifs against the MT-II template